Homepage feature slider with promotional content

Cubano New Strains

Banner image showcasing four cannabis strains from Cubano Cannabis against a black background with ornate gold corners. From left to right, the strains are: Montana Silvertip (Sativa – GDP x Super Silver Haze), Lilac Diesel (Hybrid – Silver Lemon Haze x Forbidden Fruit x NY Cherry Pie x Citral Glue), Snoop Dogg OG (Indica/Hybrid – Lemon OG x Sour Diesel), and Banana Daddy (Hybrid – GDP x Banana Hammock). Each strain is represented by a close-up of its vibrant, trichome-covered bud. The Cubano Cannabis logo is centered at the top.

Apply for Opportunities at Root 66

Banner announcing job applications are now open. Visit the jobs tab to apply and join our team.

Enjoy 10% Off on Medical Tuesdays

Unlock a 10% discount every Tuesday for all medical patients. Elevate your Root 66 experience with exclusive savings on premium products.

Cubano Extracts – Always in Stock

Cubano Cannabis logo centered in a frame with buds growing on each side. Text states Always available at Root 66.

Ostara bundle deals

Ostara Cannabis and Root 66 logos on a pot field background. Buy More Save More! .5g vape cart $23.99, 2 for $44.99, 3 for $64.99. 1g vape cart $39.99, 2 for $74.99, 3 for $99.99. 100mg OG gummies $9.99. 200mg Gummies $21.99, 2 for $39.99. 750mg gummies $64.99, 2 for $166.99. Live resin, Rise, Rest, and Balance gummies $19.99, 2 for $34.99. Star Tabs $34.99, 2 for $64.99. Galaxy Tabs $14.99, 2 for $26.99. 1g disposable $44.99, 2 for $84.99, 3 for $199.99. Can’t be combined with other offers or discounts, While Supplies Last.

Rest Gummies

The right side shows a table with lavender flowers in a vase, a lamp, lit small candle, and a package of Ostara Rest gummies. The left side has a purple background with Ostara Cannabis logo at the top, then states, Tired of counting sheep? Ask about Rest Gummies. Below are outlines of sheep jumping over a fence, drawn in light purple.

Root 66 St. Peters 24/7

Root 66 St. Peters now open 24/7 with a Walk-up Window.  3004 S. St. Peters Pkwy, St. Charles, MO 63303

Displayed on a background, half green and half red brick with a walkup window built into it.  Root 66 Dispensary logo centered at the top of the image.

Ostara Summer Solstice Sale

A bright and colorful summer-themed promotional banner for Ostara Cannabis. The image features fresh fruits, salad, and Ostara edible product packaging on a picnic blanket. Bold text in the center reads “30% off all Ostara edibles – SUMMER solstice,” with the promotion dates “June 14–20” displayed in yellow and white in the bottom right corner. The Ostara logo appears in the top right. The overall vibe is sunny, fresh, and seasonal.

Discover OSTARA Cannabis at Root 66

Promotional banner stating Ostara Cannabis is consistently stocked and available at Root 66.

Daily Deals

Graphic banner showing the Root 66 dispensary “Daily Deals” schedule alongside colorful gummy visuals and product packaging. Each day features a specific 20% off deal:

  • Sunday: Live Resin Gummies

  • Monday: Balance Gummies

  • Tuesday: Super High Dose 750mg Gummies

  • Wednesday: High Dose 200mg Gummies

  • Thursday: Rise Gummies

  • Friday: Rest Gummies

  • Saturday: Cubano Flower

Logos for Root 66, Ostara Cannabis, and Cubano Cannabis are displayed at the top. Decorative gummy images border the left and right sides. Asterisked note reads: “*All deals can’t be combined with any other discounts or offers. All deals are while supplies last.

June 2025 Sales

Promotional graphic for Root 66 Dispensary featuring June 2025 cannabis deals. The image has a dark background with green and white text blocks and logos of partnered brands. Each deal is displayed on a tag-style banner with the discount and dates:

  • Dirty River Records (June 1–July 1): 10% off in-store purchases with proof of Dirty River Records receipt.

  • Head Change (June 2–15): 20% off all live resin sauce carts; $90 bundle includes 2 live resin concentrates and a 0.5g preroll.

  • Proper (June 6–8): Badder BOGO deal for $5.26.

  • Cubano (June 14–20): 30% off all Cubano prerolls.

  • Ostara (June 14–20): 30% off all Ostara edibles.

  • SafeBet (June 16–30): 15% off all SafeBet prerolls.

  • Airo (June 17–23): 15% off all Airo pods.

Footnote: Offers cannot be stacked and are only valid during the specified dates while supplies last.

Cubano June 2025 Preroll Deal

Promotional banner for Cubano Cannabis featuring a 30% off discount on prerolls. The image shows two cannabis prerolls in front of a maroon Cubano-branded tube with bold text reading “30% OFF PREROLLS.” A red ribbon on the right side displays the promotion dates: June 14–20.

Missouri Owned Grown Rooted

The St Louis arch and riverway in the background with a bright blue sky and summer green foliage. Overlayed with text saying Missouri Owned, Grown, Rooted.

Exclusive Discounts Available! Veterans, Industry Workers, Early Birds, & Seniors 60+ – Ask Us!

Banner encouraging customers to inquire about available discounts for Veterans, Industry Workers, Early Birds, and Seniors 60+.

Dogtown Drive Thru

Dogtown location drive thru open till 12am.  Pre-orders only.

Ostara On The Go $3.99

Green background with Ostara On The Go written. Featuring a 2 pack of mystery flavor gummies in a blue package appearing to burst from multi colored fluid. These two packs are $3.99.

LOCATIONS

DES PERES

12095 Manchester Rd.
Des Peres, MO 63131
8 AM - 10 PM
 
 

DOGTOWN

6660 Manchester Ave.
St. Louis, MO 63139
8 AM - 10 PM
(Drive-Thru: 8 AM - 12 AM)
 

SOUTH GRAND

3737 S. Grand Blvd.
St. Louis, MO 63118
8 AM - 10 PM
 
 

ST. PETERS

3004 S. St. Peters Pkwy
St. Peters, MO 63303
24/7
(walk-up window 12AM-7:59AM)
 

WENTZVILLE

1163 Wentzville Pkwy
Wentzville, MO 63385
8 AM - 10 PM
 
 

 

Root 66 Road Crew Rewards logo in tan on a green background

Get Rewards, New Product Alerts, Flash Sales and More!

Get Your
Missouri Medical Marijuana
Card Online Now at

Apply for a Missouri Medical Marijuana Card with NuggMD

For Assistance Click Here

Get Your
Missouri Medical Marijuana
Card Online Now

Apply for a Missouri Medical Marijuana Card with NuggMD

For assistance Click Here

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Easily track your Highway Miles earned with every purchase, shop your favorite store, place a pre-order, rate and review past purchases, and stay updated on exclusive deals—all from the convenience of your phone.

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Download
The Root 66 Mobile App today!

Easily track your Highway Miles earned with every purchase, shop your favorite store,
place a pre-order, rate and review past purchases, and stay updated on exclusive deals—
all from the convenience of your phone.

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