DES PERES
12095 Manchester Rd.
Des Peres, MO 63131
Open Everyday 8 AM - 10 PM
About Des Peres Root 66
Welcome to our newest Root 66 location at 12095 Manchester in Des Peres, MO 63131! We are thrilled to have become a part of this vibrant and beautiful city since our grand opening in September 2023. Nestled in a convenient spot, our Des Peres location is strategically placed to provide you with easy access to our wide range of products. The city's charm and welcoming atmosphere make it an ideal setting for a Root 66 store, and we are excited to be a part of the community.
At Root 66 Des Peres, our dedicated team is here to serve you and ensure you have the best experience possible. Feel free to explore our product offerings, and don't hesitate to approach our knowledgeable budtenders with any questions you may have. We are committed to providing excellent customer service and assisting you in finding the perfect products to meet your needs. We look forward to being your go-to destination for all things Root 66 in Des Peres!
Find us at Root 66 Dispensary Des Peres, located at 12095 Manchester Rd, Des Peres, MO 63131. Click here for directions.
Our Store Manager’s
Top Picks
Meet Mike Carroll, the welcoming face behind our Des Peres location. With years of experience in the cannabis industry and a deep passion for helping our customers discover the perfect products, Mike has some standout recommendations for you.
"I’ve been working in Missouri’s cannabis industry since 2023, bringing with me more than 20 years of experience working in professional kitchens. Cannabis has become both a personal and professional passion for me. As a recreational consumer and someone who uses cannabis to help manage pain in my knees and back from those years of demanding kitchen work, I understand firsthand how it can positively impact people’s lives. What I enjoy most about working in the cannabis industry is the satisfaction of helping people. Whether I’m helping someone find the right product, answering questions, or simply making their experience a little easier, I take pride in being someone people can turn to for honest, knowledgeable guidance."
Mike Carroll
Favorite Consumption Method:
Concentrates and Rosin Vapes
Must-Try Strain:
Amaze Orange, Blueberry Clementine, and Cubano French Royale
When did you start working for Root 66?
April 2023
Grow with Us
Cultivate Your Career in Cannabis with Root 66. Join our passionate team and be part of the journey that’s shaping the future of the cannabis industry.
Google Reviews
Rebel 420Trustindex verifies that the original source of the review is Google.
This was my first visit to this dispensary. Cedric helped me and he was a delight…the entire staff was very friendly and welcoming, including the guard. I also love that they have a pet food donation box. This will definitely be my favorite place.
Josh MarshallAlways good energy when I come in. Good stock, great prices.
Jason KochAlways super fast and friendly, great selection! Mimi was super helpful as well :)
Jenn WMy favorite store in the world! Employees are happy and helpful. I love the wide range of options and something for every price range.
Charles JacksonKatie was awesome and super helpful! It's a great place!
