About South Grand Root 66
Our Root 66 South Grand location was the first medical marijuana dispensary to open in the City of St. Louis. South Grand has a flavor all its own. You can travel around the world on South Grand, known locally and regionally as an International District, the neighborhood offers a wide array of activity from unique stores and eclectic shops to a huge array of ethic restaurants.
Root 66 is proud to join the South Grand community and offer patients a wide variety of cannabis products including: cannabis flower, vapes, concentrates, edibles, beverages and more! We pride ourselves on our commitment to the community of South Grand and St. Louis to offer the best experience and widest selection in town.
Rebel 420This was my first visit to this dispensary. Cedric helped me and he was a delight…the entire staff was very friendly and welcoming, including the guard. I also love that they have a pet food donation box. This will definitely be my favorite place.
Josh MarshallAlways good energy when I come in. Good stock, great prices.
Jason KochAlways super fast and friendly, great selection! Mimi was super helpful as well :)
Jenn WMy favorite store in the world! Employees are happy and helpful. I love the wide range of options and something for every price range.
Charles JacksonKatie was awesome and super helpful! It's a great place!
