DOGTOWN

6660 Manchester Ave.
St. Louis, MO 63139

Open Everyday 8 AM - 12 AM
(Drive-Thru: Mon–Wed 8 AM – 12 AM,
Thu–Sat 8 AM – 1 AM)

Exterior of the Dogtown store featuring the drive-thru.
Back entrance of the Dogtown location with a door and an arrow directing customers.
Vibrant mural on the back of the building displaying "The Hill" with a colorful background.
Side mural of the Dogtown store featuring "St. Louis" in bold white letters against a bright background.
Close-up of a store shelf stocked with various merchandise.
Inside the backroom, showcasing a large logo sign on a brick wall, a digital menu, and a glass counter.
Wider shot of the backroom, highlighting the glass counter display and a customer queue area with a ribbon and post divider.
Another store section featuring a display case with a "Manchester Ave" street sign and clothing merchandise; an adjacent wall showcases an ATM and a black-and-white artistic Route 66 sign depicting an asphalt road.
Root66-Dogtown-01
Root66-Dogtown-02
Root66-Dogtown-03
Root66-Dogtown-04
Root66-Dogtown-06
Root66-Dogtown-07
Root66-Dogtown-08
Root66-Dogtown-09
previous arrow
next arrow
Root66-Dogtown-01
Root66-Dogtown-02
Root66-Dogtown-03
Root66-Dogtown-04
Root66-Dogtown-06
Root66-Dogtown-07
Root66-Dogtown-08
Root66-Dogtown-09
previous arrow
next arrow

About Dogtown Root 66

Our Dogtown Root 66 store was one of the first medical marijuana dispensary to open to patients in the City of St. Louis. Dogtown is recognized as a vibrant district with great food, bars and entertainment. Because of its Irish heritage, Dogtown is the location of the St. Patrick’s Day Parade that is always held on March 17th each year to huge fanfare.

Root 66 is honored to join the historic Dogtown community and offer local patients a wide variety of cannabis products including: cannabis flower, vapes, concentrates, edibles, beverages and more! We pride ourselves on our commitment to the City of St. Louis, to offer the best experience and widest selection in town.

Find us at Root 66 Dispensary Dogtown, located at 6660 Manchester Ave., St. Louis, MO 63139. Click here for directions.

Our Store Manager’s

Top Picks

Meet Cedric Kelley, the welcoming face behind our Dogtown location. With a strong understanding of cannabis and a passion for the plant, Cedric is excited to share his knowledge and help customers find their perfect product.

“Cannabis has played an important role in my life, particularly as a way to manage everyday stress and promote relaxation. I have developed a strong appreciation for cannabis and its potential benefits, including its ability to support appetite and help individuals manage certain symptoms such as nausea and inflammation. Outside of work, cannabis is also part of how I unwind and enjoy my free time. For example, playing NBA 2K26 or Call of Duty while enjoying Crema by Cubano can be a relaxing and enjoyable experience. Overall, my passion for cannabis, customer service, and the industry has given me an opportunity to turn something I genuinely enjoy into a career where I can make a positive impact on others.”

Cedric Kelley

Favorite Consumption Method:

Flower (I roll nice sized joints)

Must-Try Strain:

GMO, Blueberry Clementine, Miami Punch, Crema, and Trainwreck

When did you start working for Root 66?

March 2023

Cedric Kelley - Dogtown Store Manager. A cannabis leaf is in the bottom corner of the image.

Grow with Us

Cultivate Your Career in Cannabis with Root 66. Join our passionate team and be part of the journey that’s shaping the future of the cannabis industry.

Google Reviews

Google
Rebel 420 profile picture
Rebel 420
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
This was my first visit to this dispensary. Cedric helped me and he was a delight…the entire staff was very friendly and welcoming, including the guard. I also love that they have a pet food donation box. This will definitely be my favorite place.
Google
Josh Marshall profile picture
Josh Marshall
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Always good energy when I come in. Good stock, great prices.
Google
Jason Koch profile picture
Jason Koch
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Always super fast and friendly, great selection! Mimi was super helpful as well :)
Google
Jenn W profile picture
Jenn W
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
My favorite store in the world! Employees are happy and helpful. I love the wide range of options and something for every price range.
Google
Charles Jackson profile picture
Charles Jackson
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Katie was awesome and super helpful! It's a great place!

High Times on Instagram:
Follow Our Journey